Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease
Identifieur interne : 002B62 ( Main/Exploration ); précédent : 002B61; suivant : 002B63Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease
Auteurs : Ali Samii [États-Unis] ; Valerie E. Kelly [États-Unis] ; Jefferson C. Slimp [États-Unis] ; Anne Shumway-Cook [États-Unis] ; Robert Goodkin [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-07-30.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Chirurgie.
English descriptors
- KwdEn :
- Activities of Daily Living, Adult, Aged, Comparative study, Deep brain stimulation, Disability Evaluation, Dyskinesia, Electric Stimulation (methods), Electric Stimulation Therapy (methods), Electrodes, Implanted, Female, Functional Laterality, Humans, Male, Middle Aged, Nervous system diseases, Parkinson Disease (pathology), Parkinson Disease (surgery), Parkinson disease, Severity of Illness Index, Stimulator, Subthalamic Nucleus (physiopathology), Subthalamic nucleus, Surgery, deep brain stimulation, dyskinesia, staged surgery, subthalamic nucleus.
- MESH :
- methods : Electric Stimulation, Electric Stimulation Therapy.
- pathology : Parkinson Disease.
- physiopathology : Subthalamic Nucleus.
- surgery : Parkinson Disease.
- Activities of Daily Living, Adult, Aged, Disability Evaluation, Electrodes, Implanted, Female, Functional Laterality, Humans, Male, Middle Aged, Severity of Illness Index.
Abstract
In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On‐medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off‐medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in off‐medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21554
Affiliations:
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Le document en format XML
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<term>Adult</term>
<term>Aged</term>
<term>Comparative study</term>
<term>Deep brain stimulation</term>
<term>Disability Evaluation</term>
<term>Dyskinesia</term>
<term>Electric Stimulation (methods)</term>
<term>Electric Stimulation Therapy (methods)</term>
<term>Electrodes, Implanted</term>
<term>Female</term>
<term>Functional Laterality</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Nervous system diseases</term>
<term>Parkinson Disease (pathology)</term>
<term>Parkinson Disease (surgery)</term>
<term>Parkinson disease</term>
<term>Severity of Illness Index</term>
<term>Stimulator</term>
<term>Subthalamic Nucleus (physiopathology)</term>
<term>Subthalamic nucleus</term>
<term>Surgery</term>
<term>deep brain stimulation</term>
<term>dyskinesia</term>
<term>staged surgery</term>
<term>subthalamic nucleus</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Subthalamic Nucleus</term>
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<keywords scheme="MESH" xml:lang="en"><term>Activities of Daily Living</term>
<term>Adult</term>
<term>Aged</term>
<term>Disability Evaluation</term>
<term>Electrodes, Implanted</term>
<term>Female</term>
<term>Functional Laterality</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Severity of Illness Index</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Chirurgie</term>
<term>Dyskinésie</term>
<term>Etude comparative</term>
<term>Noyau sousthalamique</term>
<term>Parkinson maladie</term>
<term>Stimulateur</term>
<term>Stimulation cérébrale profonde</term>
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<front><div type="abstract" xml:lang="en">In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On‐medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off‐medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in off‐medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation. © 2007 Movement Disorder Society</div>
</front>
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<name sortKey="Samii, Ali" sort="Samii, Ali" uniqKey="Samii A" first="Ali" last="Samii">Ali Samii</name>
<name sortKey="Shumway Ook, Anne" sort="Shumway Ook, Anne" uniqKey="Shumway Ook A" first="Anne" last="Shumway-Cook">Anne Shumway-Cook</name>
<name sortKey="Slimp, Jefferson C" sort="Slimp, Jefferson C" uniqKey="Slimp J" first="Jefferson C." last="Slimp">Jefferson C. Slimp</name>
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